Antioxidants, Free Full-Text
Por um escritor misterioso
Last updated 11 julho 2024
![Antioxidants, Free Full-Text](https://www.mdpi.com/antioxidants/antioxidants-12-01540/article_deploy/html/images/antioxidants-12-01540-g008.png)
Age-related macular degeneration (AMD) is a complex, progressive degenerative retinal disease. Retinal pigment epithelial (RPE) cells play an important role in the immune defense of the eye and their dysfunction leads to the progressive irreversible degeneration of photoreceptors. Genetic factors, chronic inflammation, and oxidative stress have been implicated in AMD pathogenesis. Oxidative stress causes RPE injury, resulting in a chronic inflammatory response and cell death. The Y402H polymorphism in the complement factor H (CFH) protein is an important risk factor for AMD. However, the functional significance of CFH Y402H polymorphism remains unclear. In the present study, we investigated the role of CFH in the pro-inflammatory response using an in vitro model of oxidative stress in the RPE with the at-risk CFH Y402H variant. ARPE-19 cells with the at-risk CFH Y402H variant were highly susceptible to damage caused by oxidative stress, with increased levels of inflammatory mediators and pro-apoptotic factors that lead to cell death. Pretreatment of the ARPE-19 cell cultures with exogenous CFH prior to the induction of oxidative stress prevented damage and cell death. This protective effect may be related to the negative regulation of pro-inflammatory cytokines. CFH contributes to cell homeostasis and is required to modulate the pro-inflammatory cytokine response under oxidative stress in the ARPE-19 cells with the at-risk CFH Y402H variant.
![Antioxidants, Free Full-Text](https://www.perque.com/wp-content/uploads/2021/05/Blog-Post-MAY-2021-Antioxidants-vs-free-radicals.jpg)
Antioxidants vs. Free Radicals: Plant Power for the win!
![Antioxidants, Free Full-Text](https://www.researchgate.net/publication/320461663/figure/fig3/AS:676934388297729@1538405143477/The-antioxidant-system-in-cells-Enzymatic-and-nonenzymatic-antioxidants-catalyze.png)
The antioxidant system in cells. Enzymatic and nonenzymatic
![Antioxidants, Free Full-Text](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs12944-019-0969-8/MediaObjects/12944_2019_969_Fig1_HTML.png)
Antioxidant properties of Milk and dairy products: a comprehensive
![Antioxidants, Free Full-Text](https://jcp.bmj.com/content/jclinpath/54/3/176/F2.large.jpg)
Antioxidants in health and disease
![Antioxidants, Free Full-Text](https://onlinelibrary.wiley.com/cms/asset/5e1f5bca-876b-49cc-9c5a-41643b42a68d/jpi12360-fig-0008-m.jpg)
Melatonin as an antioxidant: under promises but over delivers
![Antioxidants, Free Full-Text](https://d3i71xaburhd42.cloudfront.net/162a2b26ae37c18cb0d8ef875f581d57538c6108/4-Figure1-1.png)
PDF] Free Radicals, Antioxidants in Disease and Health
![Antioxidants, Free Full-Text](https://pub.mdpi-res.com/antioxidants/antioxidants-09-00695/article_deploy/html/images/antioxidants-09-00695-ag-550.jpg?1596442609)
Flavonoid Free Radical - Colaboratory
![Antioxidants, Free Full-Text](https://i1.rgstatic.net/publication/283319344_In_vitro_antioxidant_and_free_radical_scavenging_activity_of_different_parts_of_Tabebuia_pallida_growing_in_Bangladesh/links/5fc364d8a6fdcc6cc67f3e5b/largepreview.png)
PDF) In vitro antioxidant and free radical scavenging activity of
Antioxidant Mechanism of Betaine without Free Radical Scavenging
![Antioxidants, Free Full-Text](https://www.frontiersin.org/files/Articles/552535/fphys-11-00694-HTML-r1/image_m/fphys-11-00694-g002.jpg)
Frontiers Lifestyle, Oxidative Stress, and Antioxidants: Back
![Antioxidants, Free Full-Text](https://pub.mdpi-res.com/antioxidants/antioxidants-12-01452/article_deploy/html/images/antioxidants-12-01452-g001-550.jpg?1689757694)
Chicken Invaders 9 Free Download By Zohaib Soft - Colaboratory
Recomendado para você
-
Mythical Crasher, woomy-arras.io Wiki11 julho 2024
-
Fanon:The Sentinel, Diep.io Wiki11 julho 2024
-
Triangle Sanctuary, woomy-arras.io Wiki11 julho 2024
-
diep io arena closer 3D Models to Print - yeggi11 julho 2024
-
Arras:Polygons (Woomy), Diep.io Wiki11 julho 2024
-
Drevepsina on Steam11 julho 2024
-
A new 3D descriptor for human classification: application for human detection in a multi-kinect system11 julho 2024
-
Video activation of prefrontal cortex in a consuming person during11 julho 2024
-
arrasio/arrasio/config.json at master · nepphhh/arrasio · GitHub11 julho 2024
-
Plastic end-of-life alternatives, with a focus on the agricultural sector - ScienceDirect11 julho 2024
você pode gostar
-
hello its free Foto de roupas, Roblox, Papeis de parede azuis11 julho 2024
-
Conheça o Baianinho de Mauá, ex-pedreiro que ganha R$400 mil por11 julho 2024
-
Jack Ü / Skrillex / Diplo: Skrillex and Diplo Present Jack Ü Album Review11 julho 2024
-
Noragami Aragoto:. by yoneyu on DeviantArt11 julho 2024
-
Is residual volume a synonym for dead space volume? If not, then11 julho 2024
-
Scarlet Nexus 2 Could Be Made for a More Mature Audience11 julho 2024
-
Give you 5000 steam points for 10 dollars by Steamstore11 julho 2024
-
Call of Duty: Modern Warfare 2- How to Play the Beta11 julho 2024
-
Balas @haziq01732a Game ppsspp android part 4 #ppsspp #ppsspp_game11 julho 2024
-
superman: Henry Cavill to return as Superman after cameo in Dwayne11 julho 2024