Cancers, Free Full-Text
Por um escritor misterioso
Last updated 03 setembro 2024
![Cancers, Free Full-Text](https://www.mdpi.com/cancers/cancers-15-04185/article_deploy/html/images/cancers-15-04185-g002.png)
The use of 18F-PSMA-1007 and the role of PET/MR in the diagnosis of prostate cancer are not conclusively confirmed. There are reports indicating the potential pros and cons of using 18F-PSMA-1007 as well as the PET/MR technique in prostate cancer recurrence, but they are not yet included in the EAU guidelines. The aim of the study was to assess the effectiveness of 18F-PSMA-1007 PET/MR in detecting BCR lesions at very low PSA levels <0.5 ng/mL. Methods: Sixty patients with BCR after radical prostatectomy (RP) with PSA ranged 0.1–0.5 ng/mL were enrolled in a prospective study. All patients underwent simultaneous whole-body and pelvic 18F-PSMA-1007 PET/MR. The obtained results were verified by 12-month follow-up. Results: Fifty-three lesions were detected in 45 patients with 75% detection rate. The mean PSA value was 0.31 ng/mL. Of all PSMA-positive foci, 91% were localized in the pelvis, and only 9% of lesions were located in the extrapelvic region. Local recurrences were detected in 29%, PSMA-positive lymph nodes were detected in 64% of patients and bone metastases lesions were detected in 7% of patients. Conclusions: 18F-PSMA-1007 PET/MR seems to be an excellent diagnostic tool in patients with early BCR with very low PSA levels, especially with dt PSA < 6 months. The synergistic effect of combining 18F-PSMA-1007 and whole-body PET/MR with precise multiparametric assessment of pelvic lesions is of particular benefit in early BCR.
![Cancers, Free Full-Text](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/2022/nejm_2022.386.issue-25/nejmoa2201445/20220627/images/img_small/nejmoa2201445_f0.jpeg)
PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced
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Pan-cancer whole-genome comparison of primary and metastatic solid
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Cancers, Free Full-Text
![Cancers, Free Full-Text](https://www.cancer.gov/sites/g/files/xnrzdm211/files/styles/ncids_promo_16x9/public/cgov_image/ncids_promo_art_16x9/2023-06/NCP%2016-9.png?itok=Fv-fYyDo)
Comprehensive Cancer Information - NCI
![Cancers, Free Full-Text](https://img.freepik.com/free-psd/breast-cancer-awareness-editable-text-effect_47987-13695.jpg)
Free PSD Breast cancer awareness editable text effect
from Flow Cytometry to Cytomics, Page 2
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6 versus 12 months of adjuvant trastuzumab for HER2-positive early
![Cancers, Free Full-Text](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/2022/nejm_2022.387.issue-2/nejmoa2204619/20221114/images/img_medium/nejmoa2204619_f0.jpeg)
Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C
![Cancers, Free Full-Text](https://www.mdpi.com/cancers/cancers-05-01469/article_deploy/html/images/cancers-05-01469-g003-1024.png)
Cancers, Free Full-Text
![Cancers, Free Full-Text](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/2021/nejm_2021.384.issue-25/nejmoa2103695/20211129/images/img_medium/nejmoa2103695_f0.jpeg)
Sotorasib for Lung Cancers with KRAS p.G12C Mutation
![Cancers, Free Full-Text](https://pub.mdpi-res.com/cancers/cancers-05-00015/article_deploy/html/images/cancers-05-00015-g001.png?1408018947)
Cancers, Free Full-Text
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