Cells, Free Full-Text

The primary cilium has gone from being a vestigial organelle to a crucial signaling hub of growing interest given the association between a group of human disorders, collectively known as ciliopathies, and defects in its structure or function. In recent years many ciliogenesis proteins have been observed at extraciliary sites in cells and likely perform cilium-independent functions ranging from regulation of the cytoskeleton to vesicular trafficking. Perhaps the most striking example is the non-ciliated T lymphocyte, in which components of the ciliary machinery are repurposed for the assembly and function of the immunological synapse even in the absence of a primary cilium. Furthermore, the specialization traits described at the immunological synapse are similar to those seen in the primary cilium. Here, we review common regulators and features shared by the immunological synapse and the primary cilium that document the remarkable homology between these structures.

Cells, Free Full-Text

Cells, Free Full-Text

Rapid cell-free forward engineering of novel genetic ring oscillators

Cells, Free Full-Text

The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides. - Abstract - Europe PMC

Sequencing of Circulating Cell-free DNA during Pregnancy

Cell-free Macromolecular Synthesis

Cell-free mutant analysis combined with structure prediction of a lasso peptide biosynthetic protein B2

Experimental design of upsidedown, upside-up, and cell-free control

Labile coat: reason for noninfectious cell-free varicella-zoster virus in culture. - Abstract - Europe PMC

Cancers, Free Full-Text

PDF) Protein structural biology using cell-free platform from wheat germ