IJMS, Free Full-Text
Por um escritor misterioso
Last updated 13 julho 2024
![IJMS, Free Full-Text](https://www.mdpi.com/ijms/ijms-24-13070/article_deploy/html/images/ijms-24-13070-g001.png)
Before the late 1980s, ideas around how the lipophilic phytocannabinoids might be working involved membranes and bioenergetics as these disciplines were “in vogue”. However, as interest in genetics and pharmacology grew, interest in mitochondria (and membranes) waned. The discovery of the cognate receptor for tetrahydrocannabinol (THC) led to the classification of the endocannabinoid system (ECS) and the conjecture that phytocannabinoids might be “working” through this system. However, the how and the “why” they might be beneficial, especially for compounds like CBD, remains unclear. Given the centrality of membranes and mitochondria in complex organisms, and their evolutionary heritage from the beginnings of life, revisiting phytocannabinoid action in this light could be enlightening. For example, life can be described as a self-organising and replicating far from equilibrium dissipating system, which is defined by the movement of charge across a membrane. Hence the building evidence, at least in animals, that THC and CBD modulate mitochondrial function could be highly informative. In this paper, we offer a unique perspective to the question, why and how do compounds like CBD potentially work as medicines in so many different conditions? The answer, we suggest, is that they can modulate membrane fluidity in a number of ways and thus dissipation and engender homeostasis, particularly under stress. To understand this, we need to embrace origins of life theories, the role of mitochondria in plants and explanations of disease and ageing from an adaptive thermodynamic perspective, as well as quantum mechanics.
![IJMS, Free Full-Text](https://pub.mdpi-res.com/ijms/ijms-12-07199/article_deploy/html/images/ijms-12-07199f1-1024.png?1403143417)
IJMS, Free Full-Text
![IJMS, Free Full-Text](https://www.mdpi.com/ijms/ijms-16-02879/article_deploy/html/images/ijms-16-02879-g001-1024.png)
IJMS, Free Full-Text
![IJMS, Free Full-Text](https://pub.mdpi-res.com/polymers/polymers-15-01876/article_deploy/html/images/polymers-15-01876-g001.png?1681450031)
IJMS Free Full-Text Research Advances In Mechanical, 52% OFF
![IJMS, Free Full-Text](https://pub.mdpi-res.com/ijms/ijms-15-07711/article_deploy/html/images/ijms-15-07711f1-1024.png?1403149245)
IJMS, Free Full-Text
![IJMS, Free Full-Text](https://i.pinimg.com/736x/24/c3/fd/24c3fd92af46bbfe67034cc62dc77ed8.jpg)
Pat Testing Labels Template Unique Ijms Free Full Text Genome
![IJMS, Free Full-Text](https://pub.mdpi-res.com/ijms/ijms-15-03640/article_deploy/html/images/ijms-15-03640f1-1024.png?1403148577)
IJMS, Free Full-Text
![IJMS, Free Full-Text](https://external-preview.redd.it/ijms-free-full-text-mitochondrial-dysfunction-altered-v0-SuImaE7KNg--ozGS5kqsUlHl-0V2f6imv1_fWMRyTNo.jpg?auto=webp&s=9c807f410983358f02b21dc6b537738c103ec399)
IJMS, Free Full-Text
Ijms Free Full Text Neural And Hormonal Basis Of 49680
![IJMS, Free Full-Text](https://www.mdpi.com/ijms/ijms-10-02763/article_deploy/html/images/ijms-10-02763f1-1024.png)
IJMS, Free Full-Text
![IJMS, Free Full-Text](https://pub.mdpi-res.com/ijms/ijms-14-04854/article_deploy/html/images/ijms-14-04854f1-1024.png?1403145882)
IJMS, Free Full-Text
![IJMS, Free Full-Text](http://www.mdpi.com/ijms/ijms-22-08311/article_deploy/html/images/ijms-22-08311-g005.png)
Ijms Free Full Text Neural And Hormonal Basis Of 49680
Recomendado para você
-
Replying to @aidan.52 hesitations- Shiloh dynasty chords . For13 julho 2024
-
How to Play Losing Interest - Shiloh - Guitar Tabs13 julho 2024
-
🎸Blackbird - The Beatles Guitar Tutorial with Tabs and Chords13 julho 2024
-
Canciones y Letras para Acústica, PDF13 julho 2024
-
UNFORGETTABLE Chords - Natalie Cole - E-Chords13 julho 2024
-
Bufonídeos Pululantes - Item - World of Warcraft13 julho 2024
-
Scooby doo mystery incorporated night terrors full episode13 julho 2024
-
Versão acústica de Times like these - Foo Fighters que lembrei que13 julho 2024
-
Ryan Printup13 julho 2024
-
Realistic Headgears Pitch-Mockup (Rook, Twitch, Capitão, Valkyrie13 julho 2024
você pode gostar
-
Animated GIF generator from Picsart makes AI fun again13 julho 2024
-
DIY Board Game Craft for Kids13 julho 2024
-
Buffon vai à Serie B para fechar ciclo no Parma após ganhar tudo13 julho 2024
-
isekai meikyuu de harem wo quente|Pesquisa do TikTok13 julho 2024
-
Petz Monkeyz House - Nintendo DS : Video Games13 julho 2024
-
Alphabet Lore Plush (WC Portal Part 2)13 julho 2024
-
Akuma no Mi: Goro Goro no Mi, Wiki RPG The Omniverse - Another Reality13 julho 2024
-
Como jogar Uno All Wild13 julho 2024
-
Hangman' Film Review – The Hollywood Reporter13 julho 2024
-
UEFA Champions League on X: 📅 #OTD in 2008, the first of many for @Cristiano Ronaldo 🥇🏆 #UCLfinal13 julho 2024