GPC2-CAR T cells tuned for low antigen density mediate potent
Por um escritor misterioso
Last updated 31 agosto 2024
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S1535610821006589-gr7.jpg)
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S0959804923006494-gr1.jpg)
Adoptive cell therapy in paediatric extracranial solid tumours: current approaches and future challenges - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S1535610821006589-gr5.jpg)
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://onlinelibrary.wiley.com/cms/asset/4e5b065f-7dcb-4280-ba9f-806f00c1a6b1/ijc34635-fig-0001-m.jpg)
Mechanisms and strategies for safe chimeric antigen receptor T‐cell activity control - Stock - 2023 - International Journal of Cancer - Wiley Online Library
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13046-023-02838-3/MediaObjects/13046_2023_2838_Fig12_HTML.png)
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41586-023-05707-3/MediaObjects/41586_2023_5707_Fig2_HTML.png)
CAR immune cells: design principles, resistance and the next generation
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S2666634023001368-fx1.jpg)
A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://jitc.bmj.com/content/jitc/11/1/e005881/F2.large.jpg)
Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://ars.els-cdn.com/content/image/1-s2.0-S2666379121001300-gr4.jpg)
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice - ScienceDirect
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13046-023-02838-3/MediaObjects/13046_2023_2838_Fig5_HTML.png)
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://www.researchgate.net/publication/367065322/figure/fig2/AS:11431281112747249@1673529606483/GPC2-CAR-T-cell-manufacturing-yields-proliferating-and-cytotoxic-effector-T-cells-A_Q320.jpg)
PDF) Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
![GPC2-CAR T cells tuned for low antigen density mediate potent](https://pub.mdpi-res.com/cancers/cancers-15-01171/article_deploy/html/images/cancers-15-01171-ag.png?1677028932)
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