The Habsburg jaw can be attributed to inbreeding - https

Prognathism - Wikipedia

Figure 1 from Retrognathic maxilla in Habsburg jaw. Skeletofacial analysis of Joanna of Austria (1547-1578).

Centuries of inbreeding among European royals caused the deformity known as the 'Habsburg jaw

inbreeding – News Stories About inbreeding - Page 1

Orthodontics Inc. of Yuma - Generation after generation of the Hapsburg family, who ruled across Europe for 650 years, were defined by their distinctive appearance and jutting jaws.

Inbreeding between royalty led to facial defects

A real game of thrones - The Habsburg Jaw

Charles II, Habsburg of Spain: What exactly was up with his DNA?

Centuries of inbreeding among European royals responsible for famous facial deformities seen in historical paintings