Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development
Por um escritor misterioso
Last updated 30 julho 2024
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/acsinfecdis.3c00151/asset/images/large/id3c00151_0003.jpeg)
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/jm5011397/asset/images/medium/jm-2014-011397_0009.gif)
Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41573-022-00521-4/MediaObjects/41573_2022_521_Fig4_HTML.png)
Targeting RNA structures with small molecules
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/aidcbc.2023.9.issue-10/asset/aidcbc.2023.9.issue-10.largecover.jpg)
ACS Infectious Diseases
Discovery of a Novel Class of Orally Active Trypanocidal N- Myristoyltransferase Inhibitors
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/acsinfecdis.3c00332/asset/images/medium/id3c00332_0003.gif)
ACS Infectious Diseases
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://www.researchgate.net/publication/339507703/figure/fig2/AS:958993883209744@1605653367637/Biochemical-and-structural-evidence-for-the-NMT-activity-on-lysine-a-In-cell-Alkyne-probe_Q320.jpg)
Biochemical and structural evidence for the NMT activity on lysine a
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://www.researchgate.net/publication/221742136/figure/fig3/AS:908850291040256@1593698203346/Water-molecules-in-PDZ-domains-HTRA1-HTRA2-and-HTRA3-Selectivity-in-the-HTRA-family-of.png)
Water molecules in PDZ domains HTRA1, HTRA2, and HTRA3. Selectivity in
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://www.researchgate.net/publication/259876406/figure/fig10/AS:634250038607882@1528228401996/NMT-inhibition-results-in-loss-of-the-inner-membrane-complex-and-irreversible-loss-of.png)
NMT inhibition results in loss of the inner membrane complex and
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://europepmc.org/articles/PMC3863768/bin/emss-55735-f0001.jpg)
Design and synthesis of inhibitors of Plasmodium falciparum N- myristoyltransferase, a promising target for antimalarial drug discovery. - Abstract - Europe PMC
Identification of and Structural Insights into Hit Compounds Targeting N- Myristoyltransferase for Cryptosporidium Drug Development
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/acsinfecdis.6b00094/asset/images/large/id-2016-00094n_0002.jpeg)
Cryptosporidiosis Drug Discovery: Opportunities and Challenges
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://www.frontiersin.org/files/Articles/1236814/fcimb-13-1236814-HTML/image_m/fcimb-13-1236814-g002.jpg)
Frontiers Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/acsinfecdis.3c00151/asset/images/medium/id3c00151_0006.gif)
Identification of and Structural Insights into Hit Compounds Targeting N- Myristoyltransferase for Cryptosporidium Drug Development
![Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development](https://pubs.acs.org/cms/10.1021/acsinfecdis.6b00094/asset/images/large/id-2016-00094n_0005.jpeg)
Cryptosporidiosis Drug Discovery: Opportunities and Challenges
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