Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells
Por um escritor misterioso
Last updated 03 setembro 2024
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-019-54848-x/MediaObjects/41598_2019_54848_Fig2_HTML.png)
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://europepmc.org/articles/PMC8621755/bin/nutrients-13-03714-g004.jpg)
Natural Bioactive Compounds Targeting Epigenetic Pathways in Cancer: A Review on Alkaloids, Terpenoids, Quinones, and Isothiocyanates. - Abstract - Europe PMC
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://ars.els-cdn.com/content/image/1-s2.0-S1383571821000760-ga1.jpg)
Exposure to hypomethylating 5-aza-2′-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells - ScienceDirect
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-019-54848-x/MediaObjects/41598_2019_54848_Fig3_HTML.png)
Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-023-43219-2/MediaObjects/41598_2023_43219_Fig2_HTML.png)
Repurposing disulfiram, an alcohol-abuse drug, in neuroblastoma causes KAT2A downregulation and in vivo activity with a water/oil emulsion
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://pubs.acs.org/cms/10.1021/acs.chemrestox.7b00171/asset/images/medium/tx-2017-001717_0003.gif)
Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://ars.els-cdn.com/content/image/1-s2.0-S0753332223011150-gr4.jpg)
TET protein inhibitors: Potential and limitations - ScienceDirect
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fsrep09281/MediaObjects/41598_2015_Article_BFsrep09281_Fig1_HTML.jpg)
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://www.frontiersin.org/files/Articles/1033035/fonc-12-1033035-HTML/image_m/fonc-12-1033035-g002.jpg)
Frontiers Cross-reactivity between histone demethylase inhibitor valproic acid and DNA methylation in glioblastoma cell lines
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13072-015-0004-x/MediaObjects/13072_2015_4_Fig1_HTML.gif)
DNA demethylation by 5-aza-2′-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences, Epigenetics & Chromatin
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-023-43219-2/MediaObjects/41598_2023_43219_Fig4_HTML.png)
Repurposing disulfiram, an alcohol-abuse drug, in neuroblastoma causes KAT2A downregulation and in vivo activity with a water/oil emulsion
![Sodium valproate and 5-aza-2′-deoxycytidine differentially modulate DNA demethylation in G1 phase-arrested and proliferative HeLa cells](https://www.researchgate.net/publication/329148601/figure/fig4/AS:958467661656083@1605527906542/Integrative-analysis-of-transcriptome-vs-methylome-data-a-Schematic-diagram-depicting.png)
Integrative analysis of transcriptome vs methylome data. a Schematic
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