Análise de eficácia de acordo com valores de TMB no CheckMate 9LA

O tumor mutation burden (TMB) está potencialmente associado à eficácia clínica dos inibidores de correceptores imunes. Durante o ELCC 2022, foram apresentados os dados de eficácia da combinação de nivolumabe + ipilimumabe + quimioterapia segundo os valores de TMB tanto do tecido tumoral quanto do sangue dos pacientes.

Identification and functional annotation of risk score-related genes. A

First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in metastatic non-small cell lung cancer: CheckMate 9LA 2-year patient-reported outcomes - ScienceDirect

First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in advanced non-small cell lung cancer: a subanalysis of Asian patients in CheckMate 9LA

H. Jack West, MD on X: Long-awaited results of CheckMate-9LA, nivo/ipi w/2 cycles of chemo vs. ctrl arm of 4 cycles chemo is pos for OS benefitbut that's impressive for 2017, not

PDF) Efficacy and safety of immune checkpoint inhibitors in patients with advanced non–small cell lung cancer (NSCLC): a systematic literature review

First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in metastatic non-small cell lung cancer: CheckMate 9LA 2-year patient-reported outcomes - ScienceDirect

Ebook Livro BEM PDF, PDF, Câncer

Patient-reported outcomes with first-line nivolumab plus cabozantinib versus sunitinib in patients with advanced renal cell carcinoma treated in CheckMate 9ER: an open-label, randomised, phase 3 trial - The Lancet Oncology

Caminhos da Matemática: História, Educação e Aplicações

Biomarcadores predictivos de respuesta a los inhibidores de los puntos de control inmunitario

Oncologia Clínica: Curso Preparatório para Prova de Título de Especialista em, PDF, Câncer

First-Line Nivolumab Plus Ipilimumab With Chemotherapy Versus Chemotherapy Alone for Metastatic NSCLC in CheckMate 9LA: 3-Year Clinical Update and Outcomes in Patients With Brain Metastases or Select Somatic Mutations - ScienceDirect