Genes that Escape Silencing on the Second X Chromosome May Drive Disease

When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.

Frontiers X Inactivation and Escape: Epigenetic and Structural Features

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X inactivation and escape patterns. Before differentiation, the

X Chromosome Inactivation News, Articles

Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities - ScienceDirect

Genes that Escape Silencing on the Second X Chromosome May Drive Disease

Genes that Escape Silencing on the Second X Chromosome May Drive Disease

Gene regulation in time and space during X-chromosome inactivation

Escape genes are marked by unique mCG and mCH patterns. (A)

Genes that Escape Silencing on the Second X Chromosome May Drive Disease