Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute

The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.

Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C

The pathogenesis of Niemann–Pick type C disease: a role for

Involvement of the Choroid Plexus in the Pathogenesis of Niemann

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Marko KOSICEK, PhD, Ruđer Bošković Institute, Zagreb

Niemann–Pick type C disease: cellular pathology and

Potential treatment for Niemann-Pick type C, a rare

Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C

PDF] Molecular mechanisms of neurodegeneration in Alzheimer's

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The Neuropsychiatry of Niemann-Pick Type C Disease in Adulthood

A new regulatory mechanism of STARD1 in Niemann-Pick disease type

PDF) Impaired Retromer Function in Niemann-Pick Type C Disease Is

PDF) Impaired Retromer Function in Niemann-Pick Type C Disease Is

Solving neurodegeneration: common mechanisms and strategies for